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FATUMO'S LAB

Dr. Segun Fatumo is an Assistant Professor of Genetic Epidemiology and Bioinformatics at MRC/UVRI, Uganda and London School of Hygiene and Tropical Medicine, UK . He leads The African Computational Genomics (TACG) Research group. His group’s expertise includes but not limited to GWAS, meta-analysis, Multi-variates GWAS, Genetic Risk Score, Fine Mapping, Mendelian randomisation studies and Drug Discovery. He was recently (July 2020) awarded the prestigious Wellcome International Intermediate Fellowship to lead an innovative research programme at the MRC/UVRI and LSHTM.

Dr Fatumo’s research focuses on the genetic impact of non-communicable diseases in Africa. He is actively involved in capacity building across Africa including teaching and/or postgraduate supervision at Makerere University Uganda, the University of Sciences, Techniques, and Technology of Bamako (USTTB) Mali, and Covenant University Nigeria and the Centre for Genomics Research and Innovation, National Biotechnology Development Agency (CGRI-NABDA) in Abuja, Nigeria. He is an Associate Fellow of the Higher Education Academy (AFHEA) in the UK and teaches on MSc programmes at LSHTM and Queen Mary University of London (QMUL).

Dr Fatumo co-leads the Nigerian Non-Communicable Diseases - Genetic Heritage Study (NCD-GHS) Consortium and co-directs the Nigerian cardio-metabolic genomic study (NicGen) - A concerted effort to see over 100,000 Nigerians participate in the eponymous study, which will seek to understand the genetic basis of the highly prevalent non-Communicable Diseases (NCDs) in Nigeria such as chronic kidney, diabetes, obesity among others.

Dr Fatumo received postdoctoral training in genetic epidemiology at the University of Cambridge and Wellcome Sanger Institute and a postdoctoral fellowship in Bioinformatics at the University of Georgia, Athens, USA. Prior to that, He had postgraduate training in applied Bioinformatics at the University of Cologne, Germany and Ph.D. in Computer Science (Bioinformatics specialization) from Covenant University, Nigeria. During his Ph.D. Programme, Segun developed a model which identified twenty-two (22) potential novel drug targets against malaria, some of which have been tested and validated experimentally.

Dr. Fatumo is the Founder and pioneer President of the Nigerian Bioinformatics and Genomics Network. He is the immediate past vice-president of the African Society for Bioinformatics and Computational Biology (ASBCB).

Publications

  1. Discovery and fine-mapping of kidney function loci in first genome-wide association study in Africans. Fatumo S, Chikowore T, Kalyesubula R, Nsubuga RN, Asiki G, Nashiru O, Seeley J, Crampin AC, Nitsch D, Smeeth L, Kaleebu P, Nyirenda M, Burgess S, Franceschini N, Morris AP, Tomlinson L, Newton R. DOI: 10.1101/2020.06.09.142463

  2. The opportunity in African genome resource for precision medicine. Fatumo S. 2020 EBioMedicine

  3. Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Gurdasani D; Carstensen T; Fatumo S; Chen G; Franklin CS; Prado-Martinez J; Bouman H; Abascal F; Haber M; Tachmazidou I 2019 Cell

  4. Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits. Fatumo S; Carstensen T; Nashiru O; Gurdasani D; Sandhu M; Kaleebu P 2019 Frontiers in Genetics

  5. The Nigerian Bioinformatics and Genomics Network (NBGN): a collaborative platform to advance bioinformatics and genomics in Nigeria. Fatumo S; Ebenezer TE; Ekenna C; Isewon I; Ahmad U; Adetunji C; Oladipo EK; Adebiyi M; Adebiyi E; Nashiru O 2020 Global health, epidemiology and genomics


Principal Investigator

Assistant Professor Segun Fatumo

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